Day Minus ~ 40

Somebody wasn’t able to use his Mayo slot for the REMS Abecma protocol this month, and I got it! Abecma is the original BluebirdBio bb2121 CAR-T I tried to get years ago. Reported results haven’t been quite as good as the Carvytki that I actually got, but are pretty comparable to what is being seen with most of the bispecifics, so I’m delighted. The murine component of this CAR is perhaps different enough from the murine/llama one I got that there’s plenty of hope the ninjas will survive and multiply enough to give as good a response as I could expect from any other BCMA-directed therapy. The way things are going in the world of myeloma therapy, we probably don’t even need a year more before something novel comes along when this one fails.

Ok, so the ski trip gets cut short. I am NOT complaining.